Endocrine Abstracts

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1.Material and methods: 191 males with DM 1 type in the age of 18–55 years. The control group included 25 almost healthy males in the age 21–41 years. The compensation of DM was estimated by the level of glycosylated hemoglobin. Also, the indicators of lipid profile, glomerular filtration rate...

PCOS is characterized by abdominal obesity along with conventional diagnostic features.Objective: To assess body composition in women with PCOS and normal body weight.Materials and methods: 35 women (24±1.1 years old) with confirmed diagnosis of PCOS according to Rotterdam criteria, 27 almost healthy women (25±1.2 years old), both groups wotn normal weight. Whole Body Dual-energy X-ray Absorptiometry (DEXA Total Body) sca...

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1.One hundred and sixty three males with DM 1 type in the age of 18–55 years (39.75±9.69) with the duration of disease more than 1 year were examined. The control group included 25 almost healthy males in the age 21–41 years (34.60±7.80). The compensation of DM was estimated by the l...

Aim: To evaluate the base-line serum sICAM-1 levels among patients with GO and levels sICAM-1 at the end of 6 month follow up after different schemes of GO treatment.Material and methods: 72 patients with GO have been surveyed. Patients have been put into 4 groups depending on spent treatment: 1st group – 26 patients received methylprednisolone per os 1 mg/kg in a combination with plasmapheresis; 2nd group – 14 patients received p...

Type 2 diabetes mellitus (DM2) is often associated with obstructive sleep apnea (OSA), according to the literature. Current approach in choosing the hypoglycemic therapy is based on individualization, but do not take into account the effect on OSA. The research purpose: to evaluate the effect of various hypoglycemic agents on the characteristics of OSA in patients with type 2 diabetes.Materials and methods: The study included patients with OSA and DM2, t...

The aim of the study is the search of predictors of the development of androgen deficiency in men with 1 diabetes mellitus type 1. The study included 211 men with type 1 diabetes mellitus aged 18–55 years. The median age of men was 39.00 (30.00; 45,00) years, the median duration of diabetes mellitus type 1 was 12,00 (7,00; 22,00) years. As a result of the research, it was found that an increase in the patient’s age significantly increased the risk of developing andro...

Patients with type 2 diabetes mellitus (DM) are one of the most vulnerable categories of patients in terms of adverse outcomes of COVID-19 infection.Aim: To assess the features of laboratory and instrumental data in patients with COVID-19 and type 2 DM (unvaccinated) depending on the value of glycated hemoglobin (HbA1c) at the time of the onset of oxygen deficiency.Materials and methods: The study involved 78 patients with type 2 D...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

It is known that presence of certain genetic polymorphism plays important role in development of chronic complications in patients with type 2 diabetes (T2D).Aim: To analyze distribution of VEGF G/C polymorphisms and PAI-1 4G/5G polymorphisms in patients with T2D and IHD.Materials and methods: The following groups of studies were formed: 1 – 24 almost healthy people; 2 – 28 patients with prediabetes; 3 – 37 patients ...